Antibiotic prophylaxis in oral healthcare - the agreement between Swedish recommendations and evidence

DSpace Repository

Antibiotic prophylaxis in oral healthcare - the agreement between Swedish recommendations and evidence

Overview

Detailed record

dc.contributor.author Ellervall, Eva sv
dc.contributor.author Knutsson, Kerstin sv
dc.contributor.author Vinge, Ellen sv
dc.contributor.author Rohlin, Madeleine en_US
dc.date.accessioned 2010-09-28T12:57:41Z
dc.date.available 2010-09-28T12:57:41Z
dc.date.issued 2010
dc.identifier.issn 0007-0610 en
dc.identifier.uri http://hdl.handle.net/2043/10646
dc.description.abstract BACKGROUND: Almost all (17/20) Swedish counties have pharmaceutical committees that establish recommendations for the use of antibiotic prophylaxis in oral healthcare.Objective To evaluate the evidence for the use of antibiotic prophylaxis in oral healthcare and the agreement between Swedish recommendations and evidence. MATERIAL AND METHODS: We conducted a systematic literature search in PubMed and the Cochrane Controlled Trials Register. The MeSH terms 'antibiotic prophylaxis' and 'dentistry' were used in the database search. Abstracts were reviewed according to specific inclusion and exclusion criteria. A total of 186 articles were read in full text by the four authors independently. Data extraction and interpretation of data was carried out using a pre-defined protocol. In the end, one case-control study was included for evaluation of evidence. RESULTS: The case-control study included patients with specific cardiac conditions. The study reported a 49% protective efficacy (odds ratio: 0.51) of antibiotic prophylaxis for first-time episodes of endocarditis within 30 days of procedure. This result was not statistically significant. The quality of the evidence was low. No studies were evaluated on patients with other medical conditions. The recommendations included several cardiac and other medical conditions for which there is a lack of evidence or no evidence to support the use of antibiotic prophylaxis. CONCLUSIONS: There is a lack of evidence to support the use of antibiotic prophylaxis. To avoid the risk of adverse events from antibiotics and the risk of developing resistant bacterial strains, the use of antibiotic prophylaxis should be minimised and recommendations in Sweden should be revised to be more evidence-based. en
dc.format.extent 6
dc.language.iso eng en
dc.subject.classification Medicine en
dc.title Antibiotic prophylaxis in oral healthcare - the agreement between Swedish recommendations and evidence en
dc.type Article, peer reviewed scientific en
dc.contributor.department Malmö University. Faculty of Odontology
dc.identifier.doi 10.1038/sj.bdj.2010.107 en
dc.subject.srsc Research Subject Categories::ODONTOLOGY en
dc.relation.ispartofpublication British Dental Journal;3 en
dc.relation.ispartofpublicationvolume 208 en
dc.format.artNo E5
mahlocal.rights.oaType bronze
 Find Full text Files for download

There are no files associated with this item.

This item appears in the following Collection(s)

Overview

Search


Browse

My Account

Statistics