Nano Hydroxyapatite-coated Implants Improve Bone Nanomechanical Properties

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Nano Hydroxyapatite-coated Implants Improve Bone Nanomechanical Properties

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dc.contributor.author Coelho, Paulo G sv
dc.contributor.author Bryington, Matthew sv
dc.contributor.author Baldassarri, Marta sv
dc.contributor.author Tovar, Nick sv
dc.contributor.author Currie, Fredrik sv
dc.contributor.author Hayashi, Mariko sv
dc.contributor.author Janal, Malvin N sv
dc.contributor.author Andersson, Martin sv
dc.contributor.author Ono, Daisuke sv
dc.contributor.author Jimbo, Ryo en_US
dc.contributor.author Vandeweghe, Stefan en_US
dc.contributor.author Wennerberg, Ann en_US
dc.date.accessioned 2012-12-21T11:46:12Z
dc.date.available 2012-12-21T11:46:12Z
dc.date.issued 2012 en_US
dc.identifier.issn 0022-0345 en_US
dc.identifier.uri http://hdl.handle.net/2043/14714
dc.description.abstract Nanostructure modification of dental implants has long been sought as a means to improve osseointegration through enhanced biomimicry of host structures. Several methods have been proposed and demonstrated for creating nanotopographic features; here we describe a nanoscale hydroxyapatite (HA)-coated implant surface and hypothesize that it will hasten osseointegration and improve its quality relative to that of non-coated implants. Twenty threaded titanium alloy implants, half prepared with a stable HA nanoparticle surface and half grit-blasted, acid-etched, and heat-treated (HT), were inserted into rabbit femurs. Pre-operatively, the implants were morphologically and topographically characterized. After 3 weeks of healing, the samples were retrieved for histomorphometry. The nanomechanical properties of the surrounding bone were evaluated by nanoindentation. While both implants revealed similar bone-to-implant contact, the nanoindentation demonstrated that the tissue quality was significantly enhanced around the HA-coated implants, validating the postulated hypothesis. en_US
dc.format.extent 6
dc.language.iso eng en_US
dc.publisher Sage en_US
dc.subject.classification Medicine en_US
dc.title Nano Hydroxyapatite-coated Implants Improve Bone Nanomechanical Properties en_US
dc.type Article, peer reviewed scientific en_US
dc.contributor.department Malmö University. Faculty of Odontology
dc.identifier.doi 10.1177/0022034512463240 en_US
dc.subject.srsc Research Subject Categories::ODONTOLOGY en_US
dc.relation.ispartofpublication Journal of Dental Research;12
dc.relation.ispartofpublicationvolume 91 en_US
dc.format.ePage 1177
dc.format.sPage 1172
mahlocal.rights.oaType green
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