Experimental Investigations of Biological Lubrication at the Nanoscale : The Cases of Synovial Joints and the Oral Cavity

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Experimental Investigations of Biological Lubrication at the Nanoscale : The Cases of Synovial Joints and the Oral Cavity

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dc.contributor.author Sotres, Javier
dc.contributor.author Arnebrant, Thomas
dc.date.accessioned 2013-12-05T10:01:34Z
dc.date.available 2013-12-05T10:01:34Z
dc.date.issued 2013 en_US
dc.identifier.issn 2075-4442
dc.identifier.uri http://hdl.handle.net/2043/16216
dc.description.abstract Interactions between surfaces are ubiquitous phenomena in living organisms. Nature has developed sophisticated strategies for lubricating these systems, increasing their efficiency and life span. This includes the use of water-based lubricants, such as saliva and synovial fluid. These fluids overcome the limitations of water as a lubricant by the presence of molecules such as proteins, lipids, and polysaccharides. Such molecules may alter surface interactions through different mechanisms. They can increase viscosity enabling fluid-film lubrication. Moreover, molecules adsorb on the surfaces providing mechanisms for boundary lubrication and preventing wear. The mentioned molecules have typical sizes in the nanometer range. Their interaction, as well as the interaction with the entrapping surfaces, takes place through forces in the range of nanonewtons. It is therefore not surprising that the investigation of these systems have been boosted by development of techniques such as scanning probe microscopies and the surface force apparatus which allow studying tribological processes at the nanoscale. Indeed, these approaches have generated an enormous amount of studies over the last years. The aim of this review is to perform a critical analysis of the current stage of this research, with a main focus on studies on synovial joints and the oral cavity. en_US
dc.format.extent 30
dc.language.iso eng en_US
dc.publisher MDPI en_US
dc.subject biological lubrication en_US
dc.subject nanotribology en_US
dc.subject atomic force microscope en_US
dc.subject surface force apparatus en_US
dc.subject synovial joint en_US
dc.subject synovial fluid en_US
dc.subject oral cavity en_US
dc.subject saliva en_US
dc.subject.classification Sciences en_US
dc.title Experimental Investigations of Biological Lubrication at the Nanoscale : The Cases of Synovial Joints and the Oral Cavity en_US
dc.type Article, review peer-reviewed scientific en_US
dc.contributor.department Malmö University. Faculty of Health and Society en_US
dc.contributor.department Malmö University. Biomedical Sciences (BMV) en_US
dc.identifier.doi 10.3390/lubricants1040102 en_US
dc.subject.srsc Research Subject Categories::NATURAL SCIENCES en_US
dc.relation.ispartofpublication Lubricants;4
dc.relation.ispartofpublicationvolume 1 en_US
dc.format.ePage 131
dc.format.sPage 102
mahlocal.rights.oaType gold
mahlocal.rights.oaType green
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