Strontium-Coated Deproteinized Bovine Bone Grafting Enhances Bone Repair in Calvarial Critical Size Defects

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Strontium-Coated Deproteinized Bovine Bone Grafting Enhances Bone Repair in Calvarial Critical Size Defects

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Publication Conference other
Title Strontium-Coated Deproteinized Bovine Bone Grafting Enhances Bone Repair in Calvarial Critical Size Defects
Author Aroni, Maurício ; Oliveira, Guilherme ; Chiérici Marcantonio, Rosemary Adriana ; Stavropoulos, Andreas
Date 2016
English abstract
Objectives: To evaluate the effect of strontium (Sr) coated deproteinized bovine bone (DBB-Sr) grafting on bone healing of calvarial critical-size defects (CSD) in rats. Methods: Forty-two female rats were randomly divided into 3 groups of 14 animals each. Two CSD, 5mm in diameter, were created in the parietal bones and one defect was grafted either with DBB, or DBB-Sr1 (140μM per g OBD) or DBB-Sr2 (700μM per g OBD); the other defect remained empty as control. The amount of mineralized tissue into the CSD was evaluated by micro CT 7 and 14 days post-operatively (7 animals pr. group). One-way Anova complemented by Tukey test at the confidence level of 95% was used for the statistical analysis. Results: DBB-Sr2 presented a smaller length of residual CSD comparing to defects filled with DBB-Sr1 at 15 days (p <0.05) and to defects filled with DBB (p <0.05) or DBB-Sr1 (p <0.001) at 60 days. Further, DBB-Sr2 showed greater amount of mineralized tissue fill compered to defects implanted with DBB at 15 days (p<0.01) and to defects implanted with DBB (p<0.001) or DBB-Sr1 (p<0.001) at 60 days. Conclusions: Sr coating of DBB improved bone repair in critical-size calvarial defects in rats.
Conference
IADR General Session (22-25 June, 2016 : Seoul, Republic of Korea)
Link https://iadr.abstractarchives.com/abstract/16iags-2476421/strontium-coated-deproteinized-bovine-bone-grafting-enhances-bone-repair-in-calvarial-critical-size-defects .Icon
Language eng (iso)
Subject Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/23893 Permalink to this page
Link http://www.iadr.org/IADR/Meetings/Past-Meetings/Me... (external link to related web page)
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