Surface-imprinted fluorescence microspheres as ultrasensitive sensor for rapid and effective detection of tetracycline in real biological samples

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Surface-imprinted fluorescence microspheres as ultrasensitive sensor for rapid and effective detection of tetracycline in real biological samples

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Publication Article, peer reviewed scientific
Title Surface-imprinted fluorescence microspheres as ultrasensitive sensor for rapid and effective detection of tetracycline in real biological samples
Author Wang, Jixiang ; Cheng, Rujia ; Wang, Yunyun ; Sun, Lin ; Chen, Li ; Dai, Xiaohui ; Pan, Jianming ; Pan, Guoqing ; Yan, Yongsheng
Date 2018
English abstract
Molecularly imprinted fluorescence sensors have shown great promise in environmental or biological monitoring and due to its high stability, selectivity and sensitivity. In this study, a fluorescence surface imprinted sensor (SiO2-AF@MIPs) towards tetracycline (TC) was successfully prepared to address the shortcomings in current molecularly imprinted fluorescent sensor, such as slow response, limited detection and deteriorated performance in real complex samples. Benefited from the thin surface-imprinting layer, the SiO2-AF@MIPs sensors showed higher sensitivity (LOD low to 4.26 nM), rapid detection rate, reusable performance and excellent selectivity over several target competitors. Furthermore, the fluorescence sensor could efficiently detect TC in real biological samples, including tetracycline hydrochloride injection, human serum and swine urine. These results clearly demonstrated the potential value of this smart sensor nanomaterial in environmental monitoring and biological diagnosis. (C) 2018 Elsevier B.V. All rights reserved.
DOI https://doi.org/10.1016/j.snb.2018.02.150 (link to publisher's fulltext.)
Publisher Elsevier
Host/Issue Sensors and Actuators, B: Chemical;
Volume 263
ISSN 0925-4005
Language eng (iso)
Subject Fluorescence probe
Molecularly imprinted polymer
Fluorescein
Rapid detection
Tetracycline
Sciences
Research Subject Categories::NATURAL SCIENCES
Handle http://hdl.handle.net/2043/26638 Permalink to this page
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