Detailed analysis of health-related quality of life after out-of-hospital cardiac arrest

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Detailed analysis of health-related quality of life after out-of-hospital cardiac arrest

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Publication Article, peer reviewed scientific
Title Detailed analysis of health-related quality of life after out-of-hospital cardiac arrest
Author Bohm, Mattias ; Lilja, Gisela ; Finnbogadóttir, Hafrún ; Cronberg, Tobias ; Undén, Johan ; Friberg, Hans ; Kjærgaard, Jesper ; Nielsen, Niklas ; Wise, Matt P ; Åkerman, Eva
Date 2019
English abstract
Aim: To describe the detailed health-related quality of life (HRQoL) in survivors from the TTM-trial and to investigate potential differences related to sex and age. Methods: This is a cross-sectional study originating from a large prospective international, multicentre trial, including 442 respondents who answered the Short Form-36 item Questionnaire Health Survey version 2® (SF-36v2®) at a structured follow-up 6 months after out-of-hospital cardiac arrest (OHCA). Statistical analysis between independent groups were performed with Mann-Whitney U or Chi-square. Age was analysed primarily as a dichotomised variable. Results: Although overall physical and mental health were within the normal range, a substantial proportion of respondents had impaired function at domain-specific levels, particularly in Role-Physical (50%) and Role-Emotional (35%). Females scored significantly lower than males in; Physical Functioning (41.7 vs. 47.9, p < 0.001), Role-Physical (40.4 vs. 44.3, p = 0.02), General Health (47.0 vs. 50.5, p = 0.02), Vitality (47.2 vs. 52.7, p < 0.001), and Role-Emotional (41.5 vs. 46.2, p = 0.009). Those ≤65 years scored significantly better in Physical Functioning (47.9 vs. 44.1 p < 0.001), while those >65 years scored significantly better in Vitality (50.8 vs. 53.7, p = 0.006) and Mental Health (50.3 vs. 52.6, p = 0.04). Conclusions: Many OHCA survivors demonstrated impaired function in HRQoL at a domain level, despite most patients reporting an acceptable general HRQoL. Females reported worse HRQoL than males. Older age was associated with a worse Physical Functioning but better Vitality and Mental Health. Role-Physical and Role-Emotional aspects of health were especially affected, even when effects of age and sex where accounted for.
DOI https://doi.org/10.1016/j.resuscitation.2018.10.028 (link to publisher's fulltext.)
Publisher Elsevier
Host/Issue Resuscitation;
Volume 135
ISSN 1873-1570
Language eng (iso)
Subject Cardiac Arrest
Quality of Life
SF-36v2
cross-sectional studies
outcome
Medicine
Research Subject Categories::MEDICINE
Handle http://hdl.handle.net/2043/27050 Permalink to this page
Link to publication in DiVA Find this research publication in DiVA.
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