Prevalence of severe asthma : results from a population-based study

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Prevalence of severe asthma : results from a population-based study

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Publication Conference Poster
Title Prevalence of severe asthma : results from a population-based study
Author Rönnebjerg, Lina ; Axelsson, Malin ; Pascu, Adina ; Backman, Helena ; Kankaanranta, Hannu ; Lundbäck, Bo ; Ekerljung, Linda
Date 2019
English abstract
Introduction: Research on severe asthma based on population samples is scarce and defining severe asthma in epidemiological samples is a challenge. Aims and objectives: To investigate the prevalence and clinical features of severe asthma in a population-based study. Methods: In the West Sweden Asthma Study, a randomly selected sample (N=1172) and a separate asthma sample (N=744) underwent clinical examinations. Severe asthma required at least medium dose inhaled corticosteroids (ICS) plus a second controller or oral corticosteroids (OCS) based on GINA steps 4 and 5. The prevalence was calculated in the random sample and clinical features were assessed in the asthma sample. Asthma control was assessed with the GINA Symptom Control Tool. Results: In the random sample (mean age 50.4y, 54% women), 138 subjects had current asthma (12%) and 12 (1%) had severe asthma. In the asthma sample, 94.4% of the 72 subjects with severe asthma used ICS + LABA, 4.2% used ICS + inhaled anticholinergic and 1.4% used ICS + OCS. Subjects with severe asthma were older vs. non-severe asthma (N=672), 52.1y vs. 47.6y (p=0.02). They had both lower FEV1% of predicted, 88% vs. 97% (p<0.01) and lower FEV1/FVC%, 73% vs. 77% (p<0.01). Twice as many with severe asthma, 32% vs. 16%, had daily daytime symptoms (p<0.01) and only 19% vs. 44% had controlled asthma (p<0.01). They also had more exacerbations and emergency visits the last 12 months (p=0.01), but did not differ in terms of gender or allergy status. Conclusions: The prevalence of severe asthma on population level was 1%. Subjects with severe asthma had poorer lung function and asthma control and more symptoms than subjects with non-severe asthma.
Conference
European Respiratory Society Madrid 2019 International Congress (5-9 September 2019 : Madrid)
Link https://ers-eposter.key4events.com/145/66875.pdf .Icon
Language eng (iso)
Subject Medicine
Research Subject Categories::MEDICINE
Handle http://hdl.handle.net/2043/30415 Permalink to this page
Link https://erscongress.org/home-2019.html... (external link to related web page)
Link to publication in DiVA Find this research publication in DiVA (n/a for student publ.)
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