Professional Fluoride Varnish Treatment for Caries Control: A Systematic Review of Clinical Trials

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Professional Fluoride Varnish Treatment for Caries Control: A Systematic Review of Clinical Trials

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dc.contributor.author Petersson, Lars G
dc.contributor.author Twetman, Svante
dc.contributor.author Dahlgren, Helena
dc.contributor.author Norlund, Anders
dc.contributor.author Holm, Ann-Karin
dc.contributor.author Nordenram, Gunilla
dc.contributor.author Lagerlöf, Folke
dc.contributor.author Söder, Birgitta
dc.contributor.author Kallestål, Carina
dc.contributor.author Mejàre, Ingegerd
dc.contributor.author Axelsson, Susanna
dc.contributor.author Lingström, Peter
dc.date.accessioned 2009-03-02T10:17:35Z
dc.date.available 2009-03-02T10:17:35Z
dc.date.issued 2004
dc.identifier.issn 0001-6357 en
dc.identifier.uri http://hdl.handle.net/2043/7907
dc.description.abstract The aim of this paper was systematically to evaluate the caries-preventive effect of professional fluoride varnish treatments. A search of the literature for articles published between 1966 and August 2003 was carried out in electronic databases, reference lists of articles, and selected textbooks in accordance with the strategy of the Swedish Council on Technology Assessment in Health Care. Out of 302 identified papers, 24 randomized and controlled clinical trials comparing fluoride varnish with placebo, no active treatment or other fluoride preventive regimens of at least 2 years' study duration were included. The trials that met the inclusion criteria were assessed independently and systematically by at least two reviewers and scored from A to C according to predetermined criteria for methodology and performance. The main outcome measure was the preventive fraction expressed as a percentage. The results displayed limited evidence (evidence level 3) for the caries preventive effect of topical applications of fluoride varnishes in permanent teeth. The average prevented fraction was 30% (0-69%) when compared with untreated controls. Inconclusive evidence (evidence level 4) was found for fluoride varnish treatment in the primary dentition and in adults. This systematic review reinforces the need for future dinical research of high quality, incorporating modern concepts of dinical performance and evaluation to assess dental caries control using professional fluoride varnish. en
dc.format.extent 7
dc.language.iso eng en
dc.publisher Informa Healthcare en
dc.subject Clinical trials en
dc.subject dental caries en
dc.subject fluoride varnish en
dc.subject professional fluoride en
dc.subject systematic review en
dc.subject.classification Medicine en
dc.title Professional Fluoride Varnish Treatment for Caries Control: A Systematic Review of Clinical Trials en
dc.type Article, review en
dc.contributor.department Malmö University. Faculty of Odontology en
dc.identifier.doi 10.1080/00016350410006392 en
dc.subject.srsc Research Subject Categories::ODONTOLOGY en
dc.relation.ispartofpublication Acta Odontologica Scandinavica;3 en
dc.relation.ispartofpublicationvolume 62 en
dc.format.ePage 176
dc.format.sPage 170
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