Osteoarthritis is a common disease which affects 3-5 percent of the Swedish population. Most often the hip and knee joints are affected which are the weight-bearing joints, but other joints can also be affected. The aim of this systematic literature review is to illuminate adult patient’s experiences of osteoarthritis in daily life. The study is based on 11 qualitative and quantitative articles guided by Goodman's seven-step model as a method. The results are presentered by the theme pain and the three categories: physical disability, psychological impact and social restrictions. Pain is a common problem for patients with osteoarthritis and many patients feel pain daily. Activities of daily living such as housework, walking and limitations in leisure activities create problems in these patient’s lives. Pain and physical limitations are associated with severity of the disease. Social support is important for patient's with osteoarthritis and can reduce feelings of depression and isolation. Thus, osteoarthritis affects patients physically, mentally, socially and creates limitations in activities of daily living.