Psychometric properties of the disease-specific health-related quality of life instrument VascuQoL in a Swedish setting

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Psychometric properties of the disease-specific health-related quality of life instrument VascuQoL in a Swedish setting

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Publication Article, peer reviewed scientific
Title Psychometric properties of the disease-specific health-related quality of life instrument VascuQoL in a Swedish setting
Author Nordanstig, Joakim ; Karlsson, Jan ; Pettersson, Monica E ; Wann-Hansson, Christine
Date 2012
English abstract
Background Traditional outcome measures in peripheral arterial disease (PAD) provide insufficient information regarding patient benefit. It has therefore been suggested to add patient-reported outcome measures. The main aim of this study was to validate the Swedish Vascular Quality of Life questionnaire (VascuQoL) version, a patient-reported PAD-specific health-related quality of life (HRQoL) instrument. Methods Two-hundred PAD patients were consecutively recruited from two university hospitals. Out of the 200 subjects, 129 had intermittent claudication and 71 had critical limb ischemia. Mean age was 70 ± 9 y and 57% of the participants were male. All patients completed SF-36 and VascuQoL at the vascular outpatient clinic, when evaluated for invasive treatment. Risk factors and physiological parameters were registered. Construct validity was tested by correlation analysis versus SF-36 and was also assessed with multitrait/multi-item scaling analysis (MTMI). Sensitivity analysis regarding disease severity identification was performed. Reliability was assessed with Cronbach's alpha and responsiveness by standardized response mean (SRM) calculations. Results Significant correlations were demonstrated between relevant subscales of VascuQoL and SF- 36. MTMI showed acceptable construct validity, but some scaling-errors. VascuQoL significantly (p < 0.001) discriminated claudicants from critical limb ischemia patients. Cronbach's alpha was 0.94 and SRM 1.02 (sum score). Conclusions The Swedish version of VascuQoL is valid and quantifies central aspects of HRQoL in PAD patients. Sensitivity analysis showed high ability to differentiate between disease severity and SRM illustrated excellent responsiveness. The relative abundance of items however makes use in the everyday clinical setting somewhat difficult.
DOI https://doi.org/10.1186/1477-7525-10-45 (link to publisher's fulltext.)
Publisher BioMed Central
Host/Issue Health and Quality of Life Outcomes;
Volume 10
ISSN 1477-7525
Pages 45-52
Language eng (iso)
Subject Patient-reported outcomes
Health-related quality of life
Peripheral arterial disease
Intermittent claudication
Psychometric validation
Medicine
Research Subject Categories::INTERDISCIPLINARY RESEARCH AREAS
Handle http://hdl.handle.net/2043/14079 Permalink to this page
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