Calcifying epithelial odontogenic tumor : An updated analysis of 339 cases reported in the literature

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Calcifying epithelial odontogenic tumor : An updated analysis of 339 cases reported in the literature

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Publication Article, peer reviewed scientific
Title Calcifying epithelial odontogenic tumor : An updated analysis of 339 cases reported in the literature
Author Chrcanovic, Bruno ; Santiago Gomez, Ricardo
Date 2017
English abstract
Purpose: The aim of this study was to integrate the available data published on calcifying epithelial odontogenic tumors (CEOT) into a comprehensive analysis of its clinical and radiologic features. Materials and Methods: An electronic search was undertaken in May 2016. Eligibility criteria were publications having enough clinical, radiological and/or histological information to confirm definite diagnosis. Results: A total of 362 lesions were found, 339 with enough information were analyzed. Variants clear cells (n=33) and Langerhans cells (n=10) were rarely described in the literature, as well as lesions with malignant transformation (n=8). Central lesions (n=264) were more prevalent than their peripheral counterparts (n=24). A higher prevalence characterized the mandible, posterior region, and third and fourth decades. About 40% of the peripheral lesions showed signs of underlying bone erosion, and about half of the central ones showed signs of cortical bone perforation. Recurrence was found in all lesions (12.6%), peripheral lesions (18.8%), central lesions (11.6%), clear cell (10.7%), Langerhans cell (0%), and those with malignant transformation (42.9%). Excision or curettage was associated with the highest recurrence rate. None of the variables showed a statistically significant influence on the recurrence rate. Conclusions: The possible locally aggressive behavior of the lesions recommends a less conservative management than simple curettage. The clear cell variant shows similar demographic data and biological behavior compared to the non-variant lesions, suggesting that the presence of clear cells does not have an important clinical significance.
DOI https://doi.org/10.1016/j.jcms.2017.05.007 (link to publisher's fulltext.)
Link http://www.jcmfs.com/article/S1010-5182(17)30163-4... (external link to publication)
Publisher Elsevier
Host/Issue Journal of Cranio-Maxillofacial Surgery;8
Volume 45
ISSN 1010-5182
Pages 1117-1123
Language eng (iso)
Subject Calcifying epithelial odontogenic tumor
Pindborg tumor
Intraosseous
Extraosseous
Clinical features
Recurrence rate
Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/22675 Permalink to this page
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